| URN | urn:agi-llid:4656 |
|---|---|
| Connectivity | 333 |
| Name | MYOG |
| Description | myogenin (myogenic factor 4) |
| Notes | Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq] |
| Pathway | Skeletal Myogenesis Control |
|---|---|
| VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling | |
| VasopressinR2 -> MEF/MYOD/NFATC/MYOG signaling | |
| EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG signaling | |
| IGF1R -> MEF/MYOD/MYOG signaling | |
| TGFBR -> MEF/MYOD/MYOG signaling | |
| PPARG Targets | |
| NR1D1 Targets | |
| NR2F2 Targets | |
| AR Targets |
| Ariadne Ontology | Transcription factors |
|---|
| GO Molecular Function | transcription regulator activity |
|---|---|
| DNA binding | |
| transcription factor activity | |
| RNA polymerase II transcription factor activity, enhancer binding | |
| transcription activator activity |
| GO Cellular Component | nucleus |
|---|
| GO Biological Process | positive regulation of transcription from RNA polymerase II promoter |
|---|---|
| regulation of transcription | |
| regulation of transcription, DNA-dependent | |
| cell differentiation | |
| skeletal muscle fiber development | |
| multicellular organismal development | |
| muscle organ development | |
| skeletal muscle tissue development |
| Group | Transcription factors |
|---|---|
| nucleus | |
| transcription regulator activity | |
| DNA binding | |
| transcription factor activity | |
| RNA polymerase II transcription factor activity, enhancer binding | |
| transcription activator activity | |
| positive regulation of transcription from RNA polymerase II promoter | |
| regulation of transcription | |
| regulation of transcription, DNA-dependent | |
| cell differentiation | |
| skeletal muscle fiber development | |
| multicellular organismal development | |
| muscle organ development | |
| skeletal muscle tissue development |
| Hugo ID | 7612 |
|---|
| Human chromosome position | 1q31-q41 |
|---|
| LocusLink ID | 4656 |
|---|---|
| 17928 | |
| 29148 |
| Alias | MYF4 |
|---|---|
| bHLHc3 | |
| MYOGENIN | |
| myogenic factor 4 | |
| OTTHUMP00000039094 | |
| Myogenic factor-4; myogenin | |
| myo | |
| MYOG | |
| MYOG_HUMAN | |
| Myogenic factor-4, myogenin | |
| myogenin (myogenic factor 4) | |
| myogenic factor IV | |
| Myogenic factor MYF IV | |
| Myogenic factor MYF-4 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 159980 |
|---|
| Swiss-Prot Accession | P15173 |
|---|---|
| Q53XW6 | |
| Q9HCA4 | |
| P12979 | |
| O70425 | |
| P20428 |
| Unigene ID | Hs.2830 |
|---|---|
| Mm.16528 | |
| Rn.9465 |
| KEGG ID | mmu:17928 |
|---|---|
| rno:29148 |
| Swiss-Prot ID | MYOG_HUMAN |
|---|---|
| MYOG_MOUSE | |
| MYOG_RAT | |
| Q53XW6_HUMAN | |
| O70425_RAT |
| Cell Localization | Nucleus |
|---|
| GO ID | 0016563 |
|---|---|
| 0003700 | |
| 0030154 | |
| 0007275 | |
| 0007517 | |
| 0045944 | |
| 0006355 | |
| 0048741 | |
| 0005634 | |
| 0003677 | |
| 0003705 | |
| 0030528 | |
| 0045449 | |
| 0007519 |
| IPI ID | IPI00010313 |
|---|---|
| IPI00123096 | |
| IPI00199303 | |
| IPI00558919 |
| Mouse chromosome position | 1 72.3 cM |
|---|
| Homologene ID | 1854 |
|---|
| MGI ID | 97276 |
|---|
| Rat chromosome position | 13q13 |
|---|
| RGD ID | 620432 |
|---|