| URN | urn:agi-llid:4878 |
|---|---|
| Connectivity | 1021 |
| Name | NPPA |
| Description | natriuretic peptide precursor A |
| Notes | peptide involved in the control of fluid volume and vascular function [RGD] |
| Pathway | PPARG Targets |
|---|---|
| VDR Targets |
| Ariadne Ontology | GUC activator |
|---|
| GO Molecular Function | receptor binding |
|---|---|
| hormone activity | |
| peptide hormone receptor binding |
| GO Cellular Component | extracellular region |
|---|---|
| cytoplasm | |
| perinuclear region of cytoplasm | |
| mast cell granule | |
| nucleus |
| GO Biological Process | negative regulation of cell growth |
|---|---|
| regulation of vasodilation | |
| regulation of body fluid levels | |
| regulation of blood pressure | |
| multicellular organismal water homeostasis | |
| regulation of blood vessel size | |
| cGMP biosynthetic process |
| Group | GUC activator |
|---|---|
| extracellular region | |
| cytoplasm | |
| perinuclear region of cytoplasm | |
| mast cell granule | |
| nucleus | |
| receptor binding | |
| hormone activity | |
| peptide hormone receptor binding | |
| negative regulation of cell growth | |
| regulation of vasodilation | |
| regulation of body fluid levels | |
| regulation of blood pressure | |
| multicellular organismal water homeostasis | |
| regulation of blood vessel size | |
| cGMP biosynthetic process |
| Hugo ID | 7939 |
|---|
| Human chromosome position | 1p36.21 |
|---|
| LocusLink ID | 4878 |
|---|---|
| 230899 | |
| 24602 |
| Alias | ANF |
|---|---|
| ANP | |
| PND | |
| ATFB6 | |
| CDD-ANF | |
| natriuretic peptide precursor A | |
| pronatriodilatin | |
| OTTHUMP00000002504 | |
| OTTHUMP00000044485 | |
| atrial natriuretic peptide | |
| natriuretic peptide precursor A variant 2 | |
| RP23-128E8.2 | |
| natriuretic peptide precursor type A | |
| OTTMUSP00000010827 | |
| RATANF | |
| Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd) | |
| Prepronatriodilatin | |
| pronatriodilatin, also Anf, Pnd | |
| NPPA | |
| NATRIURETIC HORMONE | |
| Natriuretic factor | |
| CDD-ANFs | |
| Atrial natriuretic factor precursor | |
| Atrial naturetic peptide | |
| LOC90230 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 108780 |
|---|---|
| 612201 |
| Swiss-Prot Accession | P01160 |
|---|---|
| Q5JZE1 | |
| Q5FW59 | |
| O55083 | |
| P05125 | |
| B0BMW5 | |
| P01161 |
| Unigene ID | Hs.75640 |
|---|---|
| Mm.19961 | |
| Rn.2004 |
| KEGG ID | hsa:4878 |
|---|---|
| mmu:230899 | |
| rno:24602 |
| Swiss-Prot ID | ANF_HUMAN |
|---|---|
| ANF_RAT | |
| Q5JZE1_HUMAN | |
| B0BMW5_RAT | |
| Q5FW59_MOUSE |
| Cell Localization | Extracellular |
|---|
| GO ID | 0005179 |
|---|---|
| 0008217 | |
| 0050880 | |
| 0005737 | |
| 0005576 | |
| 0051428 | |
| 0005102 | |
| 0006182 | |
| 0050891 | |
| 0030308 | |
| 0050878 | |
| 0042312 | |
| 0042629 | |
| 0005634 | |
| 0048471 |
| IPI ID | IPI00221279 |
|---|---|
| IPI00872482 | |
| IPI00644997 | |
| IPI00116489 | |
| IPI00553811 | |
| IPI00327424 |
| Mouse chromosome position | 4 E2 |
|---|
| Homologene ID | 4498 |
|---|
| MGI ID | 97367 |
|---|
| Rat chromosome position | 5q36 |
|---|
| RGD ID | 3193 |
|---|