| URN | urn:agi-llid:72 |
|---|---|
| Connectivity | 160 |
| Name | ACTG2 |
| Description | actin, gamma 2, smooth muscle, enteric |
| Notes | Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues. [provided by RefSeq] |
| Pathway | RARA Targets |
|---|---|
| PPARG Targets | |
| FXR Targets | |
| AR Targets |
| Ariadne Ontology | Actomyosin based movement |
|---|---|
| Actin-based cytoskeleton assembly |
| GO Molecular Function | protein binding |
|---|---|
| nucleotide binding | |
| ATP binding |
| GO Cellular Component | cytoplasm |
|---|---|
| smooth muscle contractile fiber | |
| cytoskeleton | |
| actin cytoskeleton |
| GO Biological Process | regulation of blood pressure |
|---|---|
| vascular smooth muscle contraction |
| Group | Actomyosin based movement |
|---|---|
| Actin-based cytoskeleton assembly | |
| cytoplasm | |
| smooth muscle contractile fiber | |
| cytoskeleton | |
| actin cytoskeleton | |
| protein binding | |
| nucleotide binding | |
| ATP binding | |
| regulation of blood pressure | |
| vascular smooth muscle contraction |
| Hugo ID | 145 |
|---|
| Human chromosome position | 2p13.1 |
|---|
| LocusLink ID | 72 |
|---|---|
| 11475 | |
| 25365 |
| Alias | ACT |
|---|---|
| ACTE | |
| ACTA3 | |
| ACTL3 | |
| ACTSG | |
| actin, gamma 2 | |
| alpha-actin 3 | |
| actin-like protein | |
| smooth muscle gamma actin | |
| Actvs | |
| a-SMA | |
| SMalphaA | |
| 0610041G09Rik | |
| actin, alpha 2, smooth muscle, aorta | |
| actin, alpha, vascular smooth muscle | |
| SMGA | |
| ACTGE | |
| MGC105507 | |
| actin, gamma 2, smooth muscle, enteric | |
| alpha-smooth muscle actin | |
| gamma-enteric smooth muscle actin | |
| actin, gamma 2 propeptide | |
| Alpha-actin III | |
| actin, gamma II | |
| actin, alpha-3 | |
| actin, gamma | |
| Actin, gamma-enteric smooth muscle | |
| Actg2 | |
| RIKEN cDNA 0610041G09 gene | |
| LOC115664 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 102545 |
|---|
| Swiss-Prot Accession | P63267 |
|---|---|
| Q562S2 | |
| P62737 | |
| Q3U122 | |
| Q8CF71 | |
| P63269 |
| Unigene ID | Hs.516105 |
|---|---|
| Mm.213025 | |
| Rn.958 |
| KEGG ID | hsa:72 |
|---|---|
| mmu:11475 | |
| rno:25365 |
| Swiss-Prot ID | ACTA_MOUSE |
|---|---|
| ACTH_HUMAN | |
| ACTH_RAT |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0005524 |
|---|---|
| 0000166 | |
| 0005515 | |
| 0005737 | |
| 0005856 | |
| 0008217 | |
| 0014829 | |
| 0015629 | |
| 0030485 |
| IPI ID | IPI00025416 |
|---|---|
| IPI00117043 | |
| IPI00229224 | |
| IPI00200455 | |
| IPI00560160 |
| Mouse chromosome position | 19 C3 |
|---|
| Homologene ID | 101521 |
|---|
| MGI ID | 87909 |
|---|
| Rat chromosome position | 4q34 |
|---|
| RGD ID | 2027 |
|---|