| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5465:out-urn:agi-llid:9572::positive |
|---|---|
| References | 4 |
| Connectivity | 2 |
| Effect | positive |
| CellLineName | HepG 2 |
|---|---|
| TextRef | info:pmid/10076997#cont:52 |
| MedLine Reference | 10076997:10051 |
| Sentence | This deleted Rev-erba promoter construct was induced by PPARa. |
| Journal | Mol. Endocrin |
| Journal Reference | v13 i3 p400 |
| Journal Link | http://mend.endojournals.org/cgi/content/full/13/3/400 |
| Organism | Homo sapiens |
|---|---|
| TextRef | info:pmid/12021280#cont:237 |
| MedLine Reference | 12021280:10236 |
| Sentence | Alternatively, in a multi-step process, PPAR-RXR could bind a Rev-DR2 element in Rev-erbalpha gene promoter ( B ), and increase its expression ( 50 ). |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i30 p27120 |
| Journal Link | http://www.jbc.org/cgi/content/full/277/30/27120 |
| CellType | hepatocyte |
| TextRef | info:pmid/12454280#cont:201 |
|---|---|
| Organ | liver |
| MedLine Reference | 12454280:10200 |
| Sentence | Since Rev-erba expression is induced by fibrates via a PPARa-response element in the Rev-erba gene promoter ( 31 ), our results suggest that PPARa may indirectly repress apoC-III gene transcription at least in part by increasing liver Rev-erba gene expression. |
| Journal | Lipid Res |
| Journal Reference | v43 i12 p2172 |
| Journal Link | http://www.jlr.org/cgi/content/full/43/12/2172 |
| TextRef | info:pmid/12377782#cont:91 |
|---|---|
| MedLine Reference | 12377782:10090 |
| Sentence | RESULTS TOP ABSTRACT INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION REFERENCES In Vitro Translated hRORalpha1 Protein Specifically Binds to the Rev-DR2 Site of the Human Rev-erbalpha Gene Promoter-- Rev-erbalpha as well as the PPARalpha/RXRalpha heterodimer bind to the Rev-DR2 site present in the human Rev-erbalpha gene promoter ( 8 , 15 ). |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i51 p49275 |
| Journal Link | http://www.jbc.org/cgi/content/full/277/51/49275 |