| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5465:out-urn:agi-llid:5948::positive |
|---|---|
| References | 5 |
| Connectivity | 2 |
| Effect | positive |
| CellLineName | CACO2 |
|---|---|
| TextRef | info:pmid/18797151#abs:4 |
| MedLine Reference | 18797151:3 |
| Sentence | Additionally, arachidonic acid induced in vitro binding of both PPAR alpha-RXR alpha and PPAR delta-RXR alpha heterodimers to several PPREs on CRBPII, L-FABP and ACO genes. |
| TextRef | info:pmid/11370670#abs:8 |
|---|---|
| Organ | small bowel |
| MedLine Reference | 11370670:7 |
| Sentence | These results suggest that the transcriptions of CRBPII, L-FABP, and the other PPAR-dependent genes in the small intestine may be coordinately regulated by the disproportional expression of PPARalpha and PPARdelta. |
| CellLineName | CACO2 |
|---|---|
| TextRef | info:pmid/9496708#abs:7 |
| MedLine Reference | 9496708:6 |
| Sentence | In conclusion, our data suggested that the CRBP(II) gene expression may be enhanced by an activation of PPARalpha-RXRalpha heterodimer through some putative metabolite(s) formed via fatty acid-related metabolic pathway in the clofibrc acid-treated cells. |
| TextRef | info:pmid/9575843#cont:23 |
|---|---|
| MedLine Reference | 9575843:10022 |
| Sentence | Therefore, we hypothesized that the CRBP II gene expression might be stimulated by the action of the PPAR-RXR heterodimer. |
| Journal | Gastr. Liver Phys |
| Journal Reference | v274 i4 pG626 |
| Journal Link | http://ajpgi.physiology.org/cgi/content/full/274/4/G626 |
| CellLineName | CACO2 |
|---|---|
| TextRef | info:pmid/10231366#cont:213 |
| MedLine Reference | 10231366:10212 |
| Sentence | Taken together, it is most likely that the transcriptional induction of CRBPII gene expression in Caco-2 cells induced by ETYA and 9- cis retinoic acid may be mediated by PPARalpha/RXRalpha heterodimer bound to the nuclear receptor response elements of the CRBPII gene. |
| Journal | Eur. J. Biochem |
| Journal Reference | v262 i1 p70 |
| Journal Link | http://www.ejbiochem.org/cgi/content/full/262/1/70 |