| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5465:out-urn:agi-llid:6647::unknown |
|---|---|
| References | 2 |
| Connectivity | 2 |
| Effect | unknown |
| TextRef | info:pmid/17135395#cont:231 |
|---|---|
| MedLine Reference | 17135395:10230 |
| Sentence | Supporting this interpretation, the promoter regions for catalase and Cu,Zn-SOD possess PPAR response elements ( 39 , 40 ). |
| Journal | J. Am. Soc. Nephrology |
| Journal Reference | v18 i1 p176 |
| Journal Link | http://jasn.asnjournals.org/cgi/content/full/18/1/176 |
| CellType | glomerular |
| TextRef | info:pmid/17978304#cont:143 |
|---|---|
| Organ | kidney |
| MedLine Reference | 17978304:10142 |
| Sentence | Earlier studies have reported that both catalase and Cu,Zn-SOD promoters possess PPAR response elements, 30 , 31 and that GPx-1 activity and protein amounts of Mn-SOD in KO mice are prone to decrease in the presence of various cellular injuries. 32 , 33 These earlier studies support our results, which suggests that PPARa plays an important antioxidative role in kidney through maintenance of antioxidant enzyme expression. |
| Journal | J. Am. Soc. Nephrology |
| Journal Reference | v18 i12 p3089 |
| Journal Link | http://jasn.asnjournals.org/cgi/content/full/18/12/3089 |