Expression PPARA --+> CPT1A

References 10
Connectivity 2
Effect positive
URN urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:1374::positive

MedLine Reference 16177188:2
Sentence The aim of this study was to determine whether LCFA-induced L-CPT I gene expression was mediated by PPARalpha.
CellType hepatocyte

MedLine Reference 15685545:3
Sentence PPARalpha activity was assessed by quantification of the key gene target carnitine palmitoyl acyl-CoA transferase 1 (CPT1A) messenger RNA (mRNA).The influence of HCV core protein on PPARalpha mRNA expression was analyzed in vitro by real-time PCR in HCV core-expressing HepG2 cells activated with the PPARalpha ligand fenofibric acid.
CellLineName HepG 2

Organ heart
Tissue vascular
MedLine Reference 15374828:10132
Journal Heart Circul
Journal Reference v288 i3 p1037
Journal Link http://ajpheart.physiology.org/cgi/content/full/288/3/H1037

Organ heart
Tissue skeletal muscle
MedLine Reference 16936205:10033
Journal Diabetes
Journal Reference v55 i9 p2562
Journal Link http://diabetes.diabetesjournals.org/cgi/content/full/55/9/2562

Tissue skeletal muscle
MedLine Reference 16825600:10290
Journal Cell Phys
Journal Reference v291 i2 p203
Journal Link http://ajpcell.physiology.org/cgi/content/full/291/2/C203

Organ liver
MedLine Reference 15051838:10138
Journal Nutrition
Journal Reference v134 i4 p861
Journal Link http://jn.nutrition.org/cgi/content/full/134/4/861

Organ liver
MedLine Reference 12519762:10218
Journal J. Biol. Chem
Journal Reference v278 i11 p8988
Journal Link http://www.jbc.org/cgi/content/full/278/11/8988

Organ liver
MedLine Reference 10747970:10037
Journal J. Biol. Chem
Journal Reference v275 i21 p16390
Journal Link http://www.jbc.org/cgi/content/full/275/21/16390

Organ hypothalamic
MedLine Reference 17694178:10228
Journal J Clin Invest
Journal Reference v117 i9 p2539
Journal Link http://www.jci.org/cgi/content/full/117/9/2539

Organ liver
MedLine Reference 16511589:10129
CellType myocyte
Journal J Clin Invest
Journal Reference v116 i3 p571
Journal Link http://www.jci.org/cgi/content/full/116/3/571