Expression PPARA ---| APOC3

References	10
Connectivity	2
Effect	negative
URN	urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:345::negative

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Tissue	fat
MedLine Reference	9361824:9
Sentence	PPAR directly activates genes like AOX, but also inhibits transcription of genes like S14, FAS, apolipoprotein CIII, transferrin.

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Tissue	plasma
MedLine Reference	10431661:5
Sentence	The effect of fibrates on the metabolism of triglyceride-rich lipoproteins is due to a PPAR-alpha dependent stimulation of lipoprotein lipase and an inhibition of apolipoprotein C-III expressions, whereas the increase in plasma HDL cholesterol depends on an overexpression of apolipoprotein A-I and apolipoprotein A-II.

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Tissue	serum
MedLine Reference	15087471:10122
Journal	Mol. Endocrin
Journal Reference	v18 i6 p1321
Journal Link	http://mend.endojournals.org/cgi/content/full/18/6/1321

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Tissue	plasma
MedLine Reference	14960661:10224
Journal	JPET
Journal Reference	v309 i3 p861
Journal Link	http://jpet.aspetjournals.org/cgi/content/full/309/3/861

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Tissue	plasma
MedLine Reference	11546766:10202
Journal	J. Biol. Chem
Journal Reference	v276 i44 p41293
Journal Link	http://www.jbc.org/cgi/content/full/276/44/41293

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Tissue	plasma
MedLine Reference	15001527:10115
Journal	Circulation Res
Journal Reference	v94 i7 p993
Journal Link	http://circres.ahajournals.org/cgi/content/full/94/7/993

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Organ	liver
MedLine Reference	15831517:10154
Journal	Mol. Endocrin
Journal Reference	v19 i6 p1593
Journal Link	http://mend.endojournals.org/cgi/content/full/19/6/1593

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Organ	liver
MedLine Reference	12475752:10245
Journal	Endocrin. Metabol
Journal Reference	v284 i4 pE841
Journal Link	http://ajpendo.physiology.org/cgi/content/full/284/4/E841

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Organ	liver
MedLine Reference	10774955:6

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MedLine Reference	12021280:10234
CellType	hepatocyte
Journal	J. Biol. Chem
Journal Reference	v277 i30 p27120
Journal Link	http://www.jbc.org/cgi/content/full/277/30/27120

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