| References | 10 |
|---|---|
| Connectivity | 2 |
| Effect | unknown |
| URN | urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:3569::unknown |
| MedLine Reference | 11578780:6 |
|---|---|
| Sentence | The present study explored the action of the PPAR alpha isoform and found that PPAR alpha agonists inhibited the A beta-stimulated expression of TNFalpha and IL-6 reporter genes in a dose-dependent manner. |
| CellType | macrophage |
| MedLine Reference | 11726654:10216 |
|---|---|
| Sentence | Furthermore, treatment of macrophages with PPARalpha activators in vitro is known to suppress interleukin-6 ( IL-6 ) gene transcription by interfering with NF-kappaB-driven promoter transactivation ( 32 ). |
| CellType | macrophage |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i9 p6838 |
| Journal Link | http://www.jbc.org/cgi/content/full/277/9/6838 |
| Tissue | plasma |
|---|---|
| MedLine Reference | 12874098:10033 |
| CellLineName | IIB |
| Journal | Hypertension |
| Journal Reference | v42 i4 p664 |
| Journal Link | http://hyper.ahajournals.org/cgi/content/full/42/4/664 |
| Tissue | epithelia |
|---|---|
| MedLine Reference | 15187132:10210 |
| Journal | J. Immunol |
| Journal Reference | v172 i12 p7530 |
| Journal Link | http://www.jimmunol.org/cgi/content/full/172/12/7530 |
| Tissue | endothelial |
|---|---|
| MedLine Reference | 11459775:10141 |
| Journal | Endocrinology |
| Journal Reference | v142 i8 p3332 |
| Journal Link | http://endo.endojournals.org/cgi/content/full/142/8/3332 |
| Tissue | serum |
|---|---|
| MedLine Reference | 16275545:8 |
| Organ | aorta |
|---|---|
| Tissue | smooth muscle |
| MedLine Reference | 15814532:10279 |
| CellType | hepatocyte |
| Journal | Renal Phys |
| Journal Reference | v289 i2 p469 |
| Journal Link | http://ajprenal.physiology.org/cgi/content/full/289/2/F469 |
| Tissue | smooth muscle |
|---|---|
| MedLine Reference | 12377786:10210 |
| CellType | macrophage |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i50 p48051 |
| Journal Link | http://www.jbc.org/cgi/content/full/277/50/48051 |
| Organ | aorta |
|---|---|
| Tissue | plasma |
| MedLine Reference | 11418615:10232 |
| CellType | macrophage |
| Journal | J. Biol. Chem |
| Journal Reference | v276 i36 p33471 |
| Journal Link | http://www.jbc.org/cgi/content/full/276/36/33471 |
| MedLine Reference | 12388637:10332 |
|---|---|
| CellType | macrophage |
| Journal | JPET |
| Journal Reference | v303 i2 p563 |
| Journal Link | http://jpet.aspetjournals.org/cgi/content/full/303/2/563 |