| References | 2 |
|---|---|
| Connectivity | 2 |
| Effect | unknown |
| URN | urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:355::unknown |
| Tissue | fat |
|---|---|
| MedLine Reference | 9361824:9 |
| Sentence | PPAR directly activates genes like AOX, but also inhibits transcription of genes like S14, FAS, apolipoprotein CIII, transferrin. |
| Organ | liver |
|---|---|
| MedLine Reference | 11254743:10200 |
| Sentence | First, because the expression of the genes is known to be regulated by the flux of fatty acids and cholesterol, respectively, through the liver, it is possible that PPARa indirectly influences ACC, FAS, and HMG-CoAR expression by controlling metabolic processes that affect hepatic lipid flux and, therefore, hepatic lipid concentration. |
| Journal | Lipid Res |
| Journal Reference | v42 i3 p328 |
| Journal Link | http://www.jlr.org/cgi/content/full/42/3/328 |