| References | 10 |
|---|---|
| Connectivity | 2 |
| Effect | positive |
| URN | urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:93561::positive |
| Tissue | serum |
|---|---|
| MedLine Reference | 15090553:10670 |
| Sentence | Konrad Administration of a PPAR{alpha} agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio J. |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i27 p27941 |
| Journal Link | http://www.jbc.org/cgi/content/full/279/27/27941 |
| Tissue | plasma |
|---|---|
| MedLine Reference | 15001527:10115 |
| Sentence | PPARA gene expression has been shown to affect the expression of APOA1 , APOC3 , and APOA5 . 44,45 Indeed, variation near the PPARA locus has been shown to have a modifying effect on plasma concentrations of apoC-III in FCH subjects, raising the possibility of an additional effect on plasma apoAV, which could subsequently influence triglyceride levels. 46 Lastly, we were also able to place APOA5 within the context of a previously defined FCH susceptibility haplotype at this locus. |
| Journal | Circulation Res |
| Journal Reference | v94 i7 p993 |
| Journal Link | http://circres.ahajournals.org/cgi/content/full/94/7/993 |
| MedLine Reference | 16769999:10659 |
|---|---|
| Journal | Lipid Res |
| Journal Reference | v47 i9 p2064 |
| Journal Link | http://www.jlr.org/cgi/content/full/47/9/2064 |
| MedLine Reference | 15961791:10412 |
|---|---|
| Journal | Lipid Res |
| Journal Reference | v46 i9 p2015 |
| Journal Link | http://www.jlr.org/cgi/content/full/46/9/2015 |
| MedLine Reference | 15342688:10802 |
|---|---|
| Journal | Lipid Res |
| Journal Reference | v45 i11 p2096 |
| Journal Link | http://www.jlr.org/cgi/content/full/45/11/2096 |
| Tissue | plasma |
|---|---|
| MedLine Reference | 14960661:10225 |
| Journal | JPET |
| Journal Reference | v309 i3 p861 |
| Journal Link | http://jpet.aspetjournals.org/cgi/content/full/309/3/861 |
| Tissue | plasma |
|---|---|
| MedLine Reference | 15317819:10027 |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i44 p45462 |
| Journal Link | http://www.jbc.org/cgi/content/full/279/44/45462 |
| Organ | heart |
|---|---|
| Tissue | plasma |
| MedLine Reference | 16410456:10164 |
| Journal | ATVB |
| Journal Reference | v26 i3 p590 |
| Journal Link | http://atvb.ahajournals.org/cgi/content/full/26/3/590 |
| Tissue | vascular |
|---|---|
| MedLine Reference | 15923542:10076 |
| Journal | ATVB |
| Journal Reference | v25 i6 p1097 |
| Journal Link | http://atvb.ahajournals.org/cgi/content/full/25/6/1097 |
| Tissue | plasma |
|---|---|
| MedLine Reference | 15878877:10037 |
| CellType | hepatocyte |
| CellLineName | HepG 2 |
| Journal | J. Biol. Chem |
| Journal Reference | v280 i27 p25383 |
| Journal Link | http://www.jbc.org/cgi/content/full/280/27/25383 |