Expression PPARA --+> NOS2A

References 10
Connectivity 2
Effect positive
URN urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:4843::positive

MedLine Reference 11890746:1
Sentence PPAR activation in nonadipose tissues seems to inhibit iNOS and COX2 expression.

MedLine Reference 16943204:0
Sentence Peroxisome proliferator-activated receptors (PPAR) decrease the production of cytokine and inducible nitric-oxide synthase (iNOS) expression, which are associated with aging-related inflammation and insulin resistance.

Tissue mesangia
MedLine Reference 12782627:10330
Journal J. Biol. Chem
Journal Reference v278 i32 p29799
Journal Link http://www.jbc.org/cgi/content/full/278/32/29799

MedLine Reference 12093797:10013
Journal J. Biol. Chem
Journal Reference v277 i36 p33518
Journal Link http://www.jbc.org/cgi/content/full/277/36/33518

Organ liver
MedLine Reference 16511592:10163
Journal J Clin Invest
Journal Reference v116 i3 p598
Journal Link http://www.jci.org/cgi/content/full/116/3/598

MedLine Reference 12191966:10076
CellType macrophage
CellLineName RAW264.7
Journal J. Am. Soc. Nephrology
Journal Reference v13 i9 p2223
Journal Link http://jasn.asnjournals.org/cgi/content/full/13/9/2223

Tissue peritoneal
MedLine Reference 15539630:10124
CellType macrophage
Journal Circulation Res
Journal Reference v95 i12 p1174
Journal Link http://circres.ahajournals.org/cgi/content/full/95/12/1174

MedLine Reference 12244038:10026
CellType astrocyte
Journal J. Biol. Chem
Journal Reference v277 i48 p45984
Journal Link http://www.jbc.org/cgi/content/full/277/48/45984

Organ liver
MedLine Reference 14615282:10183
CellType hepatocyte
Journal Gastr. Liver Phys
Journal Reference v286 i4 pG606
Journal Link http://ajpgi.physiology.org/cgi/content/full/286/4/G606

MedLine Reference 16397146:10106
CellType macrophage
Journal Circulation Res
Journal Reference v98 i3 p361
Journal Link http://circres.ahajournals.org/cgi/content/full/98/3/361