| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5465:out-urn:agi-llid:335::unknown |
|---|---|
| References | 2 |
| Connectivity | 2 |
| Effect | unknown |
| MedLine Reference | 11473048:10148 |
|---|---|
| Sentence | Similarly, human apo A-I gene promoter may interact with PPAR-a nuclear protein for its transcriptional regulation by fibrates ( 47 ). |
| Journal | Diabetes |
| Journal Reference | v50 i8 p1851 |
| Journal Link | http://diabetes.diabetesjournals.org/cgi/content/full/50/8/1851 |
| CellType | macrophage |
| Tissue | plasma |
|---|---|
| MedLine Reference | 12882972:10156 |
| Sentence | Fibrates are widely used hypolipidemic drugs, and they activate PPARalpha that binds to the PPRE element on the human apoA-I promoter and positively regulate the expression of apoA-I. |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i40 p38188 |
| Journal Link | http://www.jbc.org/cgi/content/full/278/40/38188 |