Expression PPARA ---> IFNG

References 8
Connectivity 2
Effect unknown
URN urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:3458::unknown

Tissue lymph
MedLine Reference 14580308:5
Sentence We recently discovered that PPARalpha transiently suppresses the transcription of gamma-interferon (IFNgamma) by inhibiting the induction of T-bet.

MedLine Reference 12816998:2
Sentence We report that activated CD4(+) T cells lacking PPARalpha produce increased levels of IFN-gamma, but significantly lower levels of IL-2 when compared with activated wild-type CD4(+) T cells.
CellType t cell

Organ artery
MedLine Reference 15578089:10101
Journal J Clin Invest
Journal Reference v114 i11 p1564
Journal Link http://www.jci.org/cgi/content/full/114/11/1564

Organ aorta
Tissue smooth muscle
MedLine Reference 15814532:10279
CellType hepatocyte
Journal Renal Phys
Journal Reference v289 i2 p469
Journal Link http://ajprenal.physiology.org/cgi/content/full/289/2/F469

Organ aorta
Tissue plasma
MedLine Reference 11418615:10232
CellType macrophage
Journal J. Biol. Chem
Journal Reference v276 i36 p33471
Journal Link http://www.jbc.org/cgi/content/full/276/36/33471

MedLine Reference 17261635:10048
CellType t cell
Journal J. Exp. Med
Journal Reference v204 i2 p321
Journal Link http://www.jem.org/cgi/content/full/204/2/321

MedLine Reference 129100940:11011
CellType t cell
Journal J. Exp. Med
Journal Reference v204 i2 p208
Journal Link http://www.jem.org/cgi/content/full/204/2/208

MedLine Reference 11934839:10059
CellType t cell
Journal Circulation Res
Journal Reference v90 i6 p703
Journal Link http://circres.ahajournals.org/cgi/content/full/90/6/703