| References | 5 |
|---|---|
| Connectivity | 2 |
| Effect | unknown |
| URN | urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-llid:4318::unknown |
| Organ | artery |
|---|---|
| Tissue | smooth muscle |
| MedLine Reference | 9831704:5 |
| Sentence | The present study tested the hypotheses that human VSMCs express PPAR alpha (PPARalpha) and PPARgamma and that PPAR agonists in VSMCs modulate MMP-9 expression and activity, as well as VSMC migration. |
| CellLineName | VSMCs |
| Organ | umbilical vein |
|---|---|
| Tissue | endothelial |
| MedLine Reference | 16230515:10089 |
| Sentence | On the other hand, PPAR activators inhibited expression of MMP-9. 56 This PPAR-dependent inhibition may prevent the rupture of atherosclerotic plaques and subsequent thrombosis. |
| CellType | macrophage |
| CellLineName | CRP+ |
| Journal | Hypertension |
| Journal Reference | v46 i5 p1086 |
| Journal Link | http://hyper.ahajournals.org/cgi/content/full/46/5/1086 |
| Organ | heart |
|---|---|
| Tissue | vascular |
| MedLine Reference | 12860836:10117 |
| Journal | Hypertension |
| Journal Reference | v42 i4 p737 |
| Journal Link | http://hyper.ahajournals.org/cgi/content/full/42/4/737 |
| MedLine Reference | 12093797:10244 |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v277 i36 p33518 |
| Journal Link | http://www.jbc.org/cgi/content/full/277/36/33518 |
| MedLine Reference | 12531895:10225 |
|---|---|
| CellType | macrophage |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i12 p10443 |
| Journal Link | http://www.jbc.org/cgi/content/full/278/12/10443 |