| URN | urn:agi-llid:2168 |
|---|---|
| Name | FABP1 |
| Description | fatty acid binding protein 1, liver |
| Connectivity | 129 |
| Notes | FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. |
| Swiss-Prot Accession | P07148 |
|---|---|
| Q6FGL7 | |
| Q05CP7 | |
| P12710 | |
| Q3V2F7 | |
| P02692 |
| Unigene ID | Hs.380135 |
|---|---|
| Mm.22126 | |
| Rn.36412 |
| KEGG ID | rno:24360 |
|---|---|
| hsa:2168 | |
| mmu:14080 |
| Swiss-Prot ID | FABPL_HUMAN |
|---|---|
| FABPL_MOUSE | |
| FABPL_RAT | |
| Q6FGL7_HUMAN | |
| Q3V2F7_MOUSE |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0003682 |
|---|---|
| 0008289 | |
| 0005215 | |
| 0009887 | |
| 0006810 | |
| 0005737 | |
| 0005634 | |
| 0005488 | |
| 0005504 | |
| 0008430 | |
| 0032052 | |
| 0008144 | |
| 0005324 | |
| 0051978 | |
| 0005543 | |
| 0050892 | |
| 0015909 | |
| 0007067 | |
| 0008284 | |
| 0032000 | |
| 0051345 | |
| 0045179 | |
| 0005829 | |
| 0005782 | |
| 0005319 | |
| 0007267 | |
| 0006631 |
| Pathway | PPARG Brief |
|---|---|
| PPARG Targets | |
| New Pathway | |
| PPARalpha Pathway |
| IPI ID | IPI00010290 |
|---|---|
| IPI00788848 | |
| IPI00120451 | |
| IPI00190790 |
| Ariadne Ontology | Lipid transport |
|---|
| Mouse chromosome position | 6 30.0 cM |
|---|
| GO Molecular Function | binding |
|---|---|
| transporter activity | |
| lipid binding | |
| chromatin binding | |
| selenium binding | |
| drug binding | |
| bile acid binding | |
| fatty acid binding | |
| phospholipid binding | |
| long-chain fatty acid transporter activity | |
| lysophospholipid transporter activity |
| Homologene ID | 1106 |
|---|
| Hugo ID | 3555 |
|---|
| GO Cellular Component | apical cortex |
|---|---|
| cytoplasm | |
| cytosol | |
| peroxisomal matrix | |
| nucleus |
| MGI ID | 95479 |
|---|
| Human chromosome position | 2p11 |
|---|
| GO Biological Process | positive regulation of cell proliferation |
|---|---|
| positive regulation of fatty acid beta-oxidation | |
| positive regulation of hydrolase activity | |
| mitosis | |
| organ morphogenesis | |
| transport | |
| long-chain fatty acid transport | |
| intestinal absorption |
| Rat chromosome position | 4q32 |
|---|
| Group | Lipid transport |
|---|---|
| apical cortex | |
| cytoplasm | |
| cytosol | |
| peroxisomal matrix | |
| nucleus | |
| binding | |
| transporter activity | |
| lipid binding | |
| chromatin binding | |
| selenium binding | |
| drug binding | |
| bile acid binding | |
| fatty acid binding | |
| phospholipid binding | |
| long-chain fatty acid transporter activity | |
| lysophospholipid transporter activity | |
| positive regulation of cell proliferation | |
| positive regulation of fatty acid beta-oxidation | |
| positive regulation of hydrolase activity | |
| mitosis | |
| organ morphogenesis | |
| transport | |
| long-chain fatty acid transport | |
| intestinal absorption |
| RGD ID | 2590 |
|---|
| LocusLink ID | 2168 |
|---|---|
| 14080 | |
| 24360 |
| Alias | FABPL |
|---|---|
| L-FABP | |
| fatty acid binding protein 1, liver | |
| Fatty acid-binding protein, liver | |
| MGC13855 | |
| OTTMUSP00000026804 | |
| fatty acid binding protein liver | |
| Fabplg | |
| MGC108756 | |
| RATFABPLG | |
| fatty acid binding protein 1 | |
| fatty-acid-binding protein | |
| liver fatty acid binding protein | |
| Fabp I | |
| FABP1 | |
| liver fatty acid-binding protein | |
| fatty acid-binding protein liver | |
| fatty acid binding protein I |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 134650 |
|---|