| URN | urn:agi-llid:1579 |
|---|---|
| Name | CYP4A11 |
| Description | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| Connectivity | 133 |
| Notes | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq] |
| Swiss-Prot Accession | Q02928 |
|---|---|
| Q16802 | |
| O88833 | |
| Q06772 | |
| Q9QYM6 | |
| A2A8T1 | |
| P08516 |
| Unigene ID | Hs.1645 |
|---|---|
| Hs.714775 | |
| Mm.10742 | |
| Rn.92401 |
| KEGG ID | hsa:1579 |
|---|---|
| mmu:13117 | |
| rno:50549 | |
| rno:170544 |
| EC Number | 1.14.15.3 |
|---|
| Swiss-Prot ID | CP4AA_RAT |
|---|---|
| CP4AB_HUMAN | |
| A2A8T1_MOUSE | |
| A2A976_MOUSE |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0018685 |
|---|---|
| 0009055 | |
| 0008393 | |
| 0020037 | |
| 0046872 | |
| 0019825 | |
| 0006631 | |
| 0055114 | |
| 0005783 | |
| 0005789 | |
| 0016020 | |
| 0005792 | |
| 0005506 | |
| 0004497 | |
| 0016491 | |
| 0008391 | |
| 0019369 | |
| 0046456 | |
| 0001822 | |
| 0048252 | |
| 0043651 | |
| 0001890 |
| Pathway | Toxicology Array |
|---|---|
| New Pathway | |
| PPARalpha Pathway |
| IPI ID | IPI00872799 |
|---|---|
| IPI00829998 | |
| IPI00646318 | |
| IPI00322218 | |
| IPI00876447 | |
| IPI00647974 | |
| IPI00405750 | |
| IPI00327623 | |
| IPI00568264 | |
| IPI00560132 | |
| IPI00782422 | |
| IPI00778609 | |
| IPI00845879 |
| Ariadne Ontology | Leukotriene synthesis |
|---|
| Mouse chromosome position | 4 49.5 cM |
|---|---|
| 4 D1 |
| GO Molecular Function | electron carrier activity |
|---|---|
| oxygen binding | |
| metal ion binding | |
| iron ion binding | |
| heme binding | |
| oxidoreductase activity | |
| monooxygenase activity | |
| fatty acid (omega-1)-hydroxylase activity | |
| arachidonic acid monooxygenase activity | |
| alkane 1-monooxygenase activity |
| Hugo ID | 2642 |
|---|
| GO Cellular Component | membrane |
|---|---|
| microsome | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum |
| MGI ID | 88611 |
|---|---|
| 3717148 |
| Human chromosome position | 1p33 |
|---|
| GO Biological Process | icosanoid biosynthetic process |
|---|---|
| fatty acid metabolic process | |
| lauric acid metabolic process | |
| linoleic acid metabolic process | |
| arachidonic acid metabolic process | |
| placenta development | |
| kidney development | |
| oxidation reduction |
| Rat chromosome position | 5q36 |
|---|
| Group | Leukotriene synthesis |
|---|---|
| membrane | |
| microsome | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| electron carrier activity | |
| oxygen binding | |
| metal ion binding | |
| iron ion binding | |
| heme binding | |
| oxidoreductase activity | |
| monooxygenase activity | |
| fatty acid (omega-1)-hydroxylase activity | |
| arachidonic acid monooxygenase activity | |
| alkane 1-monooxygenase activity | |
| icosanoid biosynthetic process | |
| fatty acid metabolic process | |
| lauric acid metabolic process | |
| linoleic acid metabolic process | |
| arachidonic acid metabolic process | |
| placenta development | |
| kidney development | |
| oxidation reduction |
| RGD ID | 71080 |
|---|---|
| 68945 |
| LocusLink ID | 1579 |
|---|---|
| 13117 | |
| 100040843 | |
| 50549 | |
| 170544 |
| Alias | CP4Y |
|---|---|
| CYP4A2 | |
| CYP4AII | |
| cytochrome P450, family 4, subfamily A, polypeptide 11 | |
| P450HL-omega | |
| OTTHUMP00000009714 | |
| alkane-1 monooxygenase | |
| fatty acid omega-hydroxylase | |
| lauric acid omega-hydroxylase | |
| cytochrome P450, subfamily IVA, polypeptide 11 | |
| RP1 | |
| Cyp4a | |
| D4Rp1 | |
| AI647584 | |
| cytochrome P450, family 4, subfamily a, polypeptide 10 | |
| OTTMUSP00000008953 | |
| cytochrome P450, 4a10 | |
| RP23-118K16.4 | |
| OTTMUSG00000008689 | |
| cytochrome P450, family 4, subfamily a, polypeptide 32 | |
| OTTMUSP00000009028 | |
| Cyp4a22 | |
| cytochrome P450, family 4, subfamily a, polypeptide 1 | |
| P450-LA-omega 1 | |
| cytochrome P452 | |
| cytochrome P450, 4A1 | |
| cytochrome P450, IVA1 | |
| cytochrome P450, family 4, subfamily A, polypeptide 22 | |
| Cyp4a10 | |
| D4Rp I | |
| Cyp4a11 | |
| Cytochrome P450 4A11 | |
| 4A2 isoform of omega-hydroxylase | |
| P-450 HK omega | |
| cytochrome P450,4A1 | |
| cytochrome P450,4A I | |
| Cyp4a1 | |
| Cytochrome P450, IVA I | |
| Cyp4a I | |
| fatty acid omega-hydroxylase CYP4A11 | |
| P450-LA-omega I | |
| 4A10 | |
| Cyp4a32 | |
| LOC100044540 | |
| LOC624900 | |
| LOC631060 | |
| LOC674313 | |
| CYPIVA11 | |
| FLJ40804 | |
| MGC25972 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 601310 |
|---|