| URN | urn:agi-llid:3389 |
|---|---|
| Name | ABCA12 |
| Description | ATP-binding cassette, sub-family A (ABC1), member 12 |
| Connectivity | 13 |
| Notes | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq] |
| Swiss-Prot Accession | Q86UK0 |
|---|---|
| Q53QE2 | |
| Q53S55 | |
| Q8BZ38 | |
| Q8C137 | |
| Q8CJA1 |
| Unigene ID | Hs.134585 |
|---|---|
| Mm.159251 |
| KEGG ID | mmu:74591 |
|---|
| Swiss-Prot ID | ABCAC_HUMAN |
|---|
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0005524 |
|---|---|
| 0016887 | |
| 0000166 | |
| 0019725 | |
| 0006869 | |
| 0016021 | |
| 0016020 | |
| 0003674 | |
| 0008150 | |
| 0005743 |
| Pathway | Toxicology Array |
|---|---|
| New Pathway | |
| PPARalpha Pathway |
| IPI ID | IPI00782981 |
|---|---|
| IPI00457109 | |
| IPI00855037 | |
| IPI00624357 | |
| IPI00224009 |
| Ariadne Ontology | Lipid export |
|---|
| Mouse chromosome position | 1 C3 |
|---|
| GO Molecular Function | molecular_function |
|---|---|
| nucleotide binding | |
| ATP binding | |
| ATPase activity |
| Homologene ID | 45441 |
|---|
| Hugo ID | 14637 |
|---|
| GO Cellular Component | membrane |
|---|---|
| mitochondrial inner membrane | |
| integral to membrane |
| MGI ID | 2676312 |
|---|
| Human chromosome position | 2q34 |
|---|
| GO Biological Process | biological_process |
|---|---|
| cellular homeostasis | |
| lipid transport |
| Group | Lipid export |
|---|---|
| membrane | |
| mitochondrial inner membrane | |
| integral to membrane | |
| molecular_function | |
| nucleotide binding | |
| ATP binding | |
| ATPase activity | |
| biological_process | |
| cellular homeostasis | |
| lipid transport |
| LocusLink ID | 3389 |
|---|---|
| 26154 | |
| 74591 |
| Alias | LI2 |
|---|---|
| ICR2B | |
| FLJ41584 | |
| DKFZp434G232 | |
| ATP-binding cassette, sub-family A, member 12 | |
| ichthyosis congenita II, lamellar ichthyosis B | |
| MGC189862 | |
| MGC189975 | |
| 4832428G11Rik | |
| 4833417A11Rik | |
| ATP-binding cassette, sub-family A (ABC1), member 12 | |
| ichthyosis congenita V, Sjogren-Larsson-like | |
| ICR5 | |
| ATP-binding cassette, sub-family A, member XII | |
| ATP-binding cassette, sub-family A, member 12 isoform b | |
| 4832428G11 | |
| ATP-binding cassette transporter family A member 12 | |
| ATP-binding cassette A12 | |
| Abca12 | |
| RIKEN cDNA 4832428G11 gene | |
| DKFZP434G232 protein | |
| RIKEN cDNA 4833417A11 gene | |
| Ichthyosis congenita II protein | |
| Abca12s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| OMIM ID | 607800 |
|---|---|
| 242500 | |
| 601277 |