| URN | urn:agi-llid:23305 |
|---|---|
| Name | ACSL6 |
| Description | acyl-CoA synthetase long-chain family member 6 |
| Connectivity | 21 |
| Notes | catalyzes the ligation of long chain fatty acids with coenzyme A to produce long chain acyl-CoAs in fatty acid metabolism [RGD] |
| Swiss-Prot Accession | Q9UKU0 |
|---|---|
| Q108M9 | |
| Q108N0 | |
| Q4G191 | |
| Q86TN7 | |
| Q8R1X1 | |
| Q5ICG4 | |
| Q91WC3 | |
| Q5ICG5 | |
| Q5F2D0 | |
| Q5ICG6 | |
| Q80TQ7 | |
| Q8BYJ0 | |
| Q8C028 | |
| P33124 | |
| Q6IU14 |
| Unigene ID | Hs.14945 |
|---|---|
| Mm.267478 | |
| Rn.33697 |
| KEGG ID | hsa:23305 |
|---|---|
| mmu:216739 |
| EC Number | 6.2.1.3 |
|---|
| Swiss-Prot ID | ACSL6_HUMAN |
|---|---|
| ACSL6_MOUSE | |
| ACSL6_RAT | |
| Q5F2D0_MOUSE | |
| Q5ICG4_MOUSE | |
| Q5ICG5_MOUSE | |
| Q8R1X1_MOUSE |
| Cell Localization | Mitochondria |
|---|
| GO ID | 0016874 |
|---|---|
| 0004467 | |
| 0000287 | |
| 0006637 | |
| 0006629 | |
| 0008152 | |
| 0005783 | |
| 0005789 | |
| 0016021 | |
| 0005792 | |
| 0005741 | |
| 0005739 | |
| 0005778 | |
| 0005777 | |
| 0005886 | |
| 0003824 | |
| 0005515 | |
| 0006631 | |
| 0007405 | |
| 0016020 | |
| 0001676 | |
| 0007584 | |
| 0043434 | |
| 0005575 | |
| 0005634 |
| Pathway | New Pathway |
|---|---|
| PPARalpha Pathway |
| IPI ID | IPI00657816 |
|---|---|
| IPI00296333 | |
| IPI00657883 | |
| IPI00879209 | |
| IPI00218718 | |
| IPI00874262 | |
| IPI00384110 | |
| IPI00657924 | |
| IPI00658107 | |
| IPI00657818 | |
| IPI00795177 | |
| IPI00796262 | |
| IPI00879154 | |
| IPI00879360 | |
| IPI00625955 | |
| IPI00649775 | |
| IPI00404113 | |
| IPI00649460 | |
| IPI00553820 | |
| IPI00553736 | |
| IPI00123390 | |
| IPI00262693 | |
| IPI00856340 | |
| IPI00880399 | |
| IPI00882185 | |
| IPI00324041 | |
| IPI00421952 | |
| IPI00776455 | |
| IPI00780414 |
| Ariadne Ontology | Fatty acid oxidation |
|---|
| Mouse chromosome position | 11 29.35 cM |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| protein binding | |
| magnesium ion binding | |
| ligase activity | |
| long-chain-fatty-acid-CoA ligase activity |
| Homologene ID | 100939 |
|---|
| Hugo ID | 16496 |
|---|
| GO Cellular Component | cellular_component |
|---|---|
| membrane | |
| microsome | |
| endoplasmic reticulum membrane | |
| mitochondrion | |
| endoplasmic reticulum | |
| peroxisome | |
| peroxisomal membrane | |
| mitochondrial outer membrane | |
| nucleus | |
| plasma membrane | |
| integral to membrane |
| MGI ID | 894291 |
|---|
| Human chromosome position | 5q31 |
|---|
| GO Biological Process | metabolic process |
|---|---|
| neuroblast proliferation | |
| fatty acid metabolic process | |
| acyl-CoA metabolic process | |
| long-chain fatty acid metabolic process | |
| lipid metabolic process | |
| response to nutrient | |
| response to peptide hormone stimulus |
| Rat chromosome position | 10q22 |
|---|
| Group | Fatty acid oxidation |
|---|---|
| cellular_component | |
| membrane | |
| microsome | |
| endoplasmic reticulum membrane | |
| mitochondrion | |
| endoplasmic reticulum | |
| peroxisome | |
| peroxisomal membrane | |
| mitochondrial outer membrane | |
| nucleus | |
| plasma membrane | |
| integral to membrane | |
| catalytic activity | |
| protein binding | |
| magnesium ion binding | |
| ligase activity | |
| long-chain-fatty-acid-CoA ligase activity | |
| metabolic process | |
| neuroblast proliferation | |
| fatty acid metabolic process | |
| acyl-CoA metabolic process | |
| long-chain fatty acid metabolic process | |
| lipid metabolic process | |
| response to nutrient | |
| response to peptide hormone stimulus |
| RGD ID | 69403 |
|---|
| LocusLink ID | 23305 |
|---|---|
| 216739 | |
| 117243 |
| Alias | ACS2 |
|---|---|
| FACL6 | |
| LACS2 | |
| LACS5 | |
| FLJ16173 | |
| KIAA0837 | |
| acyl-CoA synthetase long-chain family member 6 | |
| long fatty acyl-CoA synthetase 2 | |
| long-chain acyl-CoA synthetase 6 | |
| fatty-acid-Coenzyme A ligase, long-chain 6 | |
| LACS | |
| Lacsl | |
| AW050338 | |
| MGC36650 | |
| mKIAA0837 | |
| A330035H04Rik | |
| RP23-297J14.1 | |
| Lacs-like | |
| OTTMUSP00000005836 | |
| OTTMUSP00000005837 | |
| OTTMUSP00000005838 | |
| OTTMUSP00000005843 | |
| OTTMUSP00000023673 | |
| OTTMUSP00000029330 | |
| OTTMUSP00000029331 | |
| long-chain acyl-CoA synthetase | |
| long-chain acyl-CoA synthetase-like | |
| fatty acid Coenzyme A ligase, long chain 6 | |
| fatty-acid-Coenzyme A ligase, long-chain VI | |
| RIKEN cDNA A330035H04 gene | |
| Long-chain acyl-CoA synthetase VI | |
| long fatty acyl-CoA synthetase II | |
| LACS 6 | |
| Long-chain acyl-CoA synthetase 6 | |
| Long-chain-fatty-acid-CoA ligase 6 | |
| LACS VI | |
| LACS VIs | |
| Long-chain-fatty-acid-CoA ligase VI | |
| ACSL6 | |
| acyl-CoA synthetase long-chain family member VI |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604443 |
|---|