| URN | urn:agi-llid:6555 |
|---|---|
| Name | SLC10A2 |
| Description | solute carrier family 10 (sodium/bile acid cotransporter family), member 2 |
| Connectivity | 72 |
| Notes | mediates sodium-dependent transport of bile acids; plays a role in bile acid circulation and reabsorption; facilitates cholesterol catabolism [RGD] |
| Swiss-Prot Accession | A1L4F4 |
|---|---|
| Q12908 | |
| P70172 | |
| Q0VBB8 | |
| Q6QQR9 | |
| Q62633 | |
| Q71V65 |
| Unigene ID | Hs.194783 |
|---|---|
| Mm.3500 | |
| Rn.85891 |
| KEGG ID | hsa:6555 |
|---|---|
| mmu:20494 | |
| rno:29500 |
| Swiss-Prot ID | NTCP2_HUMAN |
|---|---|
| NTCP2_MOUSE | |
| NTCP2_RAT | |
| A1L4F4_HUMAN | |
| Q0VBB8_MOUSE |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0008508 |
|---|---|
| 0031402 | |
| 0015293 | |
| 0015721 | |
| 0006811 | |
| 0015711 | |
| 0006814 | |
| 0016324 | |
| 0005887 | |
| 0005634 | |
| 0005886 | |
| 0000502 | |
| 0006810 | |
| 0016021 | |
| 0016020 | |
| 0008206 | |
| 0022857 |
| Pathway | Figure 3 CAR 2009 |
|---|---|
| FXR Targets | |
| Toxicology Array | |
| New Pathway | |
| PPARalpha Pathway |
| IPI ID | IPI00030208 |
|---|---|
| IPI00136340 | |
| IPI00207064 |
| Ariadne Ontology | Na+ influx co-transport |
|---|---|
| OA transport |
| Mouse chromosome position | 8 2.0 cM |
|---|
| GO Molecular Function | sodium ion binding |
|---|---|
| bile acid:sodium symporter activity | |
| symporter activity |
| Homologene ID | 390 |
|---|
| Hugo ID | 10906 |
|---|
| GO Cellular Component | membrane |
|---|---|
| apical plasma membrane | |
| proteasome complex | |
| nucleus | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane |
| MGI ID | 1201406 |
|---|
| Human chromosome position | 13q33 |
|---|
| GO Biological Process | bile acid metabolic process |
|---|---|
| transport | |
| ion transport | |
| organic anion transport | |
| sodium ion transport | |
| bile acid and bile salt transport |
| Rat chromosome position | 16q12.5 |
|---|
| Group | Na+ influx co-transport |
|---|---|
| OA transport | |
| membrane | |
| apical plasma membrane | |
| proteasome complex | |
| nucleus | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane | |
| sodium ion binding | |
| bile acid:sodium symporter activity | |
| symporter activity | |
| bile acid metabolic process | |
| transport | |
| ion transport | |
| organic anion transport | |
| sodium ion transport | |
| bile acid and bile salt transport |
| RGD ID | 3682 |
|---|
| LocusLink ID | 6555 |
|---|---|
| 20494 | |
| 29500 |
| Alias | ASBT |
|---|---|
| ISBT | |
| NTCP2 | |
| solute carrier family 10 (sodium/bile acid cotransporter family), member 2 | |
| OTTHUMP00000018682 | |
| OTTHUMP00000040691 | |
| ileal sodium-dependent bile acid transporter | |
| ileal apical sodium-dependent bile acid transporter | |
| solute carrier family 10, member 2 | |
| ISBAT | |
| solute carrier family 10, member II | |
| Ileal Na(+)/bile acid cotransporter | |
| Na+ dependent ileal bile acid transporter | |
| Slc10a2 | |
| Ileal sodium-dependent bile acid transporter | |
| Sodium/taurocholate cotransporting polypeptide, ileal | |
| solute carrier family 10 (sodium/bile acid cotransporter family), member II | |
| Ileal sodium/bile acid cotransporter |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 601295 |
|---|