| References | 1 |
|---|---|
| Connectivity | 2 |
| Effect | negative |
| URN | urn:agi-Expression:inout-urn:agi-llid:5467:out-urn:agi-llid:2194::negative |
| TextRef | info:pmid/18627005#abs:6 |
|---|---|
| MedLine Reference | 18627005:5 |
| Sentence | PPARdelta inhibited the proteolytic processing of SREBP-1 into the mature active form, thereby suppressing the expression of the lipogenic genes fatty acid synthase, stearyl CoA desaturase-1, and acetyl coenzyme A carboxylase. |
| CellType | hepatocyte |