| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5467:out-urn:agi-llid:51129::positive |
|---|---|
| References | 4 |
| Connectivity | 2 |
| Effect | positive |
| CellLineName | C2C12 |
|---|---|
| TextRef | info:pmid/19074989#abs:7 |
| MedLine Reference | 19074989:6 |
| Sentence | In C2C12 myocytes, knockdown of PPARD, but not of PPARG, blocked LCFA-mediated ANGPTL4 induction, and LCFA treatment resulted in PPAR-delta recruitment to the ANGPTL4 gene. |
| CellType | myocyte |
| CellLineName | FAO |
|---|---|
| TextRef | info:pmid/15190076#cont:109 |
| MedLine Reference | 15190076:10108 |
| Sentence | The synthetic PPARß/d agonist L165041 also strongly increased FIAF mRNA, suggesting that PPARß/d stimulates FIAF gene expression too. |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i33 p34411 |
| Journal Link | http://www.jbc.org/cgi/content/full/279/33/34411 |
| TextRef | info:pmid/17893232#cont:206 |
|---|---|
| MedLine Reference | 17893232:10205 |
| Sentence | Alternatively, ligand activation of PPARß/d could inhibit tumorigenesis via induction of ANGPTL4, which can inhibit tumor cell motility and invasiveness ( 73 ). |
| Journal | Carcinogenesis |
| Journal Reference | v29 i1 p169 |
| Journal Link | http://carcin.oxfordjournals.org/cgi/content/full/29/1/169 |
| CellLineName | FAO |
|---|---|
| TextRef | info:pmid/15863837#cont:160 |
| MedLine Reference | 15863837:10159 |
| Sentence | In contrast to the expression profile of Angptl3, expression of Angptl4 in FAO cells is induced by up to 100-fold by both agonists for PPARa and PPARd/ß ( Fig. 5B ). |
| Journal | Lipid Res |
| Journal Reference | v46 i7 p1484 |
| Journal Link | http://www.jlr.org/cgi/content/full/46/7/1484 |