PromoterBinding PPARD --+> TGFB1

URN urn:agi-PromoterBinding:inout-urn:agi-llid:5467:out-urn:agi-llid:7040::positive
References 2
Connectivity 2
Effect positive

CellLineName VSMCs
Tissue smooth muscle
TextRef info:pmid/18007025#abs:4
MedLine Reference 18007025:3
Sentence The PPARdelta activator GW501516 upregulates TGF-beta1 expression in a dose- and time-dependent manner.

Organism Rattus norvegicus
Tissue smooth muscle
TextRef info:pmid/18239142#cont:18
Organ aorta
MedLine Reference 18239142:10017
Sentence PPARß/d binds to a PPAR response element in the promoter of TGFß1 to induce transcription and new protein production.
Journal Circulation Res
Journal Reference v102 i2 p146
Journal Link http://circres.ahajournals.org/cgi/content/full/102/2/146