| References | 3 |
|---|---|
| Connectivity | 2 |
| Effect | positive |
| URN | urn:agi-Expression:inout-urn:agi-llid:5467:out-urn:agi-llid:64781::positive |
| MedLine Reference | 18565104:10 |
|---|---|
| Sentence | These findings indicated that CerK gene expression was directly regulated by PPARbeta. |
| CellType | keratinocyte |
| Tissue | serum |
|---|---|
| MedLine Reference | 18565104:6 |
| Sentence | Interestingly, activation of PPARbeta enhanced the mRNA expression of CerK and CerK activity. |
| CellType | keratinocyte |
| Tissue | serum |
|---|---|
| MedLine Reference | 18565104:11 |
| Sentence | In conclusion, our results demonstrate that PPARbeta-mediated upregulation of CerK gene expression is necessary for keratinocyte survival against serum starvation-induced apoptosis. |
| CellType | keratinocyte |