| URN | urn:agi-llid:6401 |
|---|---|
| Name | SELE |
| Description | selectin, endothelial cell |
| Connectivity | 568 |
| Notes | facilitates recruitment of leukocytes into sites of inflammation; plays a role in cell adhesion [RGD] |
| Swiss-Prot Accession | A2RRD6 |
|---|---|
| P16581 | |
| Q5TI75 | |
| Q6ULR7 | |
| Q3U5F6 | |
| Q00690 | |
| P98105 |
| Unigene ID | Hs.82848 |
|---|---|
| Mm.5245 | |
| Rn.10359 | |
| Hs.89546 |
| KEGG ID | hsa:6401 |
|---|---|
| mmu:20339 | |
| rno:25544 |
| Swiss-Prot ID | LYAM2_HUMAN |
|---|---|
| LYAM2_RAT | |
| A2RRD6_HUMAN | |
| Q3U5F6_MOUSE |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0005515 |
|---|---|
| 0033691 | |
| 0005529 | |
| 0007155 | |
| 0006954 | |
| 0007159 | |
| 0005615 | |
| 0016021 | |
| 0005886 | |
| 0005488 | |
| 0016020 | |
| 0003674 | |
| 0050900 | |
| 0005575 | |
| 0007157 | |
| 0005509 |
| Pathway | SELE -> ELK-SRF signaling |
|---|---|
| Cardiovascular Disease (Large) | |
| PPARbeta Targets |
| IPI ID | IPI00296542 |
|---|---|
| IPI00514728 | |
| IPI00645768 | |
| IPI00514342 | |
| IPI00514521 | |
| IPI00225751 | |
| IPI00205215 | |
| IPI00392681 |
| Ariadne Ontology | Selectin |
|---|
| Mouse chromosome position | 1 86.6 cM |
|---|
| GO Molecular Function | molecular_function |
|---|---|
| binding | |
| protein binding | |
| sugar binding | |
| sialic acid binding |
| Homologene ID | 389 |
|---|
| Hugo ID | 10718 |
|---|
| GO Cellular Component | cellular_component |
|---|---|
| membrane | |
| plasma membrane | |
| integral to membrane | |
| extracellular space |
| MGI ID | 98278 |
|---|
| Human chromosome position | 1q22-q25 |
|---|
| GO Biological Process | cell adhesion |
|---|---|
| leukocyte adhesion | |
| leukocyte migration | |
| inflammatory response |
| Rat chromosome position | 13q22 |
|---|
| Group | Selectin |
|---|---|
| cellular_component | |
| membrane | |
| plasma membrane | |
| integral to membrane | |
| extracellular space | |
| molecular_function | |
| binding | |
| protein binding | |
| sugar binding | |
| sialic acid binding | |
| cell adhesion | |
| leukocyte adhesion | |
| leukocyte migration | |
| inflammatory response |
| RGD ID | 3654 |
|---|
| LocusLink ID | 6401 |
|---|---|
| 20339 | |
| 25544 |
| Alias | ELAM |
|---|---|
| ESEL | |
| CD62E | |
| ELAM1 | |
| LECAM2 | |
| RP1-117P20.2 | |
| selectin E | |
| OTTHUMP00000032745 | |
| endothelial adhesion molecule 1 | |
| leukocyte endothelial cell adhesion molecule 2 | |
| E-selectin | |
| selectin, endothelial cell | |
| ELAM-1 | |
| Leukocyte-endothelial cell adhesion molecule 2 | |
| Sele | |
| selectin E (endothelial adhesion molecule 1) | |
| endothelial adhesion molecule I | |
| Endothelial leukocyte adhesion molecule I | |
| Leukocyte-endothelial cell adhesion molecule II | |
| ELAM I | |
| Endothelial leukocyte adhesion molecule 1 | |
| sE-selectin | |
| E-selectin precursor | |
| LECAM2s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 131210 |
|---|---|
| 145500 | |
| 161950 |