| URN | urn:agi-llid:29881 |
|---|---|
| Name | NPC1L1 |
| Description | NPC1 (Niemann-Pick disease, type C1, gene)-like 1 |
| Connectivity | 52 |
| Swiss-Prot Accession | Q17RV5 |
|---|---|
| Q9UHC9 | |
| A8MSP5 | |
| Q6T3U4 |
| Unigene ID | Hs.567486 |
|---|---|
| Mm.212492 |
| KEGG ID | hsa:29881 |
|---|---|
| mmu:237636 |
| Swiss-Prot ID | NPCL1_HUMAN |
|---|---|
| NPCL1_MOUSE | |
| A8MSP5_HUMAN | |
| Q17RV5_HUMAN |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0008158 |
|---|---|
| 0030299 | |
| 0006695 | |
| 0030301 | |
| 0006629 | |
| 0042157 | |
| 0008202 | |
| 0016324 | |
| 0031410 | |
| 0030659 | |
| 0016021 | |
| 0005886 | |
| 0003674 | |
| 0042632 | |
| 0008203 | |
| 0005575 | |
| 0016020 |
| Pathway | PPARbeta BCL6 Targets |
|---|---|
| PPARbeta Targets |
| IPI ID | IPI00002984 |
|---|---|
| IPI00641846 | |
| IPI00640209 | |
| IPI00793281 | |
| IPI00114063 |
| Ariadne Ontology | Lipid transport |
|---|
| Mouse chromosome position | 11 A1 |
|---|
| GO Molecular Function | molecular_function |
|---|---|
| hedgehog receptor activity |
| Homologene ID | 56585 |
|---|
| Hugo ID | 7898 |
|---|
| GO Cellular Component | cellular_component |
|---|---|
| membrane | |
| apical plasma membrane | |
| cytoplasmic vesicle membrane | |
| cytoplasmic vesicle | |
| plasma membrane | |
| integral to membrane |
| MGI ID | 2685089 |
|---|
| Human chromosome position | 7p13 |
|---|
| GO Biological Process | cholesterol homeostasis |
|---|---|
| cholesterol metabolic process | |
| cholesterol biosynthetic process | |
| steroid metabolic process | |
| lipoprotein metabolic process | |
| cholesterol transport | |
| intestinal cholesterol absorption | |
| lipid metabolic process |
| Group | Lipid transport |
|---|---|
| cellular_component | |
| membrane | |
| apical plasma membrane | |
| cytoplasmic vesicle membrane | |
| cytoplasmic vesicle | |
| plasma membrane | |
| integral to membrane | |
| molecular_function | |
| hedgehog receptor activity | |
| cholesterol homeostasis | |
| cholesterol metabolic process | |
| cholesterol biosynthetic process | |
| steroid metabolic process | |
| lipoprotein metabolic process | |
| cholesterol transport | |
| intestinal cholesterol absorption | |
| lipid metabolic process |
| LocusLink ID | 29881 |
|---|---|
| 237636 |
| Alias | NPC11L1 |
|---|---|
| Niemann-Pick C1-like protein 1 | |
| Gm243 | |
| 9130221N23Rik | |
| RP23-198N14.2 | |
| OTTMUSP00000000725 | |
| Niemann-Pick disease, type C1 | |
| Niemann-Pick disease, type C1-like 1 | |
| 9130221N23 | |
| Niemann-Pick disease, type C1-like | |
| Niemann-Pick disease type C1-like 1 | |
| NPC1L1 | |
| NPC1L I | |
| Niemann-Pick disease, type C1-like I | |
| RIKEN cDNA 9130221N23 gene | |
| NPC1 (Niemann-Pick disease, type C1, gene)-like 1 | |
| NPC1-like 1 | |
| LOC278378 | |
| NPC3 | |
| hypothetical protein 9130221N23 | |
| NPC1 (Niemann-Pick disease, type C1, gene)-like | |
| Niemann-Pick C3 protein | |
| ortholog of human npc1 (niemann-pick disease, type c1, gene)-like 1 npc1l1 | |
| NPC1 (Niemann-Pick disease, type C1, gene)-like I | |
| GM 243 | |
| GM-243 | |
| GM(243) |
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| OMIM ID | 608010 |
|---|