| URN | urn:agi-llid:2167 |
|---|---|
| Name | FABP4 |
| Description | fatty acid binding protein 4, adipocyte |
| Connectivity | 95 |
| Notes | FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. |
| Swiss-Prot Accession | P15090 |
|---|---|
| Q6IBA1 | |
| P04117 | |
| Q542H7 | |
| Q99M00 | |
| Q9R290 | |
| P70623 | |
| Q5XFV4 |
| Unigene ID | Hs.391561 |
|---|---|
| Mm.582 | |
| Rn.4258 |
| KEGG ID | rno:79451 |
|---|---|
| hsa:2167 | |
| mmu:11770 |
| Swiss-Prot ID | FABP4_HUMAN |
|---|---|
| FABP4_MOUSE | |
| Q6IBA1_HUMAN | |
| Q542H7_MOUSE | |
| Q9R290_RAT |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0005504 |
|---|---|
| 0005515 | |
| 0016564 | |
| 0005215 | |
| 0042632 | |
| 0001816 | |
| 0006631 | |
| 0006469 | |
| 0016481 | |
| 0008284 | |
| 0050729 | |
| 0042493 | |
| 0051384 | |
| 0006810 | |
| 0005737 | |
| 0005829 | |
| 0005634 | |
| 0005625 | |
| 0005488 | |
| 0008289 | |
| 0050873 | |
| 0050872 |
| Pathway | PPARG Brief |
|---|---|
| PPARG Targets | |
| PPARbeta Targets |
| IPI ID | IPI00215746 |
|---|---|
| IPI00789692 | |
| IPI00116705 | |
| IPI00473910 | |
| IPI00207890 |
| Ariadne Ontology | Lipid transport |
|---|
| Mouse chromosome position | 3 13.9 cM |
|---|
| GO Molecular Function | binding |
|---|---|
| transporter activity | |
| protein binding | |
| lipid binding | |
| fatty acid binding | |
| transcription repressor activity |
| Homologene ID | 36067 |
|---|
| Hugo ID | 3559 |
|---|
| GO Cellular Component | soluble fraction |
|---|---|
| cytoplasm | |
| cytosol | |
| nucleus |
| MGI ID | 88038 |
|---|
| Human chromosome position | 8q21 |
|---|
| GO Biological Process | negative regulation of transcription |
|---|---|
| positive regulation of cell proliferation | |
| positive regulation of inflammatory response | |
| negative regulation of protein kinase activity | |
| cholesterol homeostasis | |
| brown fat cell differentiation | |
| white fat cell differentiation | |
| fatty acid metabolic process | |
| transport | |
| cytokine production | |
| response to drug | |
| response to glucocorticoid stimulus |
| Rat chromosome position | 2q23 |
|---|
| Group | Lipid transport |
|---|---|
| soluble fraction | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| binding | |
| transporter activity | |
| protein binding | |
| lipid binding | |
| fatty acid binding | |
| transcription repressor activity | |
| negative regulation of transcription | |
| positive regulation of cell proliferation | |
| positive regulation of inflammatory response | |
| negative regulation of protein kinase activity | |
| cholesterol homeostasis | |
| brown fat cell differentiation | |
| white fat cell differentiation | |
| fatty acid metabolic process | |
| transport | |
| cytokine production | |
| response to drug | |
| response to glucocorticoid stimulus |
| RGD ID | 69309 |
|---|
| LocusLink ID | 2167 |
|---|---|
| 11770 | |
| 79451 |
| Alias | aP2 |
|---|---|
| A-FABP | |
| fatty acid binding protein 4, adipocyte | |
| Lbpl | |
| 422/aP2 | |
| ALBP/Ap2 | |
| adipocyte protein aP2 | |
| lipid binding protein-like | |
| Albp | |
| fatty acid binding protein 4 | |
| adipocyte lipid-binding protein | |
| adipocyte fatty acid-binding protein | |
| adipocyte fatty acid binding protein | |
| Adipocyte lipid-binding protein | |
| AFABP | |
| fatty acid binding protein IV | |
| Fabp4 | |
| LOC360339 | |
| LOC84378 | |
| Fatty acid-binding protein, adipocyte |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600434 |
|---|