Protein DEFB4

URN urn:agi-llid:1673
Name DEFB4
Description defensin, beta 4
Connectivity 175
Notes Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq]

Swiss-Prot Accession O15263

Unigene ID Hs.105924

KEGG ID hsa:1673

Swiss-Prot ID DEFB2_HUMAN

GO ID 0007186
0006935
0042742
0006955
0005576

Pathway VDR Targets

IPI ID IPI00005739

Hugo ID 2767

GO Cellular Component extracellular region

Human chromosome position 8p23.1-p22

GO Biological Process G-protein coupled receptor protein signaling pathway
immune response
chemotaxis
defense response to bacterium

GenBank ID NC_000008
NM_004942
NP_004933
NT_077531
AC130365
AF040153
AAC33549
AF071216
AAC69554
AJ000152
CAB65126
BC069285
AAH69285
BC093983
AAH93983
BC093985
AAH93985
Z71389
CAA95992
O15263

Group extracellular region
G-protein coupled receptor protein signaling pathway
immune response
chemotaxis
defense response to bacterium

LocusLink ID 1673

Alias SAP1
DEFB2
HBD-2
DEFB-2
DEFB102
defensin, beta 4
defensin, beta 2
skin-antimicrobial peptide 1
human beta-defensin 4
beta 2 defensin
beta-defensin 4
DEFB4
defensin, beta IV
Skin-antimicrobial peptide I
defensin, beta II
Beta-defensin II
HBD II
SAP I
hbd-4
beta defensin 2
LOC115252

Organism Homo sapiens

OMIM ID 602215
266600