| URN | urn:agi-llid:9052 |
|---|---|
| Name | GPRC5A |
| Description | G protein-coupled receptor, family C, group 5, member A |
| Connectivity | 10 |
| Notes | This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq] |
| Swiss-Prot Accession | B3KV45 |
|---|---|
| Q8NFJ5 | |
| Q8BHL4 | |
| A1A5R2 | |
| Q5RK14 |
| Unigene ID | Hs.631733 |
|---|---|
| Mm.23575 | |
| Mm.477015 | |
| Rn.23566 |
| KEGG ID | hsa:9052 |
|---|---|
| rno:312790 |
| Swiss-Prot ID | RAI3_HUMAN |
|---|---|
| B3KV45_HUMAN | |
| A1A5R2_RAT |
| Cell Localization | Plasma membrane |
|---|
| GO ID | 0004930 |
|---|---|
| 0004872 | |
| 0007186 | |
| 0007165 | |
| 0005794 | |
| 0031410 | |
| 0030659 | |
| 0005783 | |
| 0005887 | |
| 0005886 | |
| 0004871 | |
| 0016021 | |
| 0016020 |
| Pathway | VDR Targets |
|---|
| IPI ID | IPI00022624 |
|---|---|
| IPI00791082 | |
| IPI00789322 | |
| IPI00321753 | |
| IPI00766316 |
| Ariadne Ontology | GPCR-Other |
|---|
| Mouse chromosome position | 6 G1 |
|---|
| GO Molecular Function | signal transducer activity |
|---|---|
| receptor activity | |
| G-protein coupled receptor activity |
| Homologene ID | 2961 |
|---|
| Hugo ID | 9836 |
|---|
| GO Cellular Component | membrane |
|---|---|
| cytoplasmic vesicle membrane | |
| cytoplasmic vesicle | |
| Golgi apparatus | |
| endoplasmic reticulum | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane |
| MGI ID | 1891250 |
|---|
| Human chromosome position | 12p13-p12.3 |
|---|
| GO Biological Process | signal transduction |
|---|---|
| G-protein coupled receptor protein signaling pathway |
| Rat chromosome position | 4q43 |
|---|
| Group | GPCR-Other |
|---|---|
| membrane | |
| cytoplasmic vesicle membrane | |
| cytoplasmic vesicle | |
| Golgi apparatus | |
| endoplasmic reticulum | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane | |
| signal transducer activity | |
| receptor activity | |
| G-protein coupled receptor activity | |
| signal transduction | |
| G-protein coupled receptor protein signaling pathway |
| RGD ID | 1310804 |
|---|
| LocusLink ID | 9052 |
|---|---|
| 232431 | |
| 312790 |
| Alias | RAI3 |
|---|---|
| RAIG1 | |
| GPCR5A | |
| G protein-coupled receptor, family C, group 5, member A | |
| retinoic acid induced 3 | |
| retinoic acid responsive | |
| OTTMUSP00000026736 | |
| MGC156777 | |
| FLJ10899 FIS | |
| GPRC5A | |
| retinoic acid induced III | |
| RAIG I |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604138 |
|---|