| URN | urn:agi-llid:632 |
|---|---|
| Name | BGLAP |
| Description | bone gamma-carboxyglutamate (gla) protein (osteocalcin) |
| Connectivity | 392 |
| Notes | highly conserved protein associated with mineralized bone matrix; protein is secreted by calcified tissues and is regulated by vitamin D3 [RGD] |
| Swiss-Prot Accession | P02818 |
|---|---|
| P54615 | |
| Q78H72 | |
| P04641 | |
| P04640 |
| Unigene ID | Hs.654541 |
|---|---|
| Mm.425160 | |
| Mm.389459 | |
| Rn.9722 |
| KEGG ID | hsa:632 |
|---|---|
| mmu:12095 | |
| mmu:12096 | |
| mmu:12097 | |
| rno:25295 |
| Swiss-Prot ID | OSTCN_HUMAN |
|---|---|
| OSTCN_RAT |
| Cell Localization | Extracellular |
|---|
| GO ID | 0005509 |
|---|---|
| 0046848 | |
| 0008147 | |
| 0007155 | |
| 0042476 | |
| 0030500 | |
| 0045124 | |
| 0045670 | |
| 0001501 | |
| 0005576 | |
| 0001503 | |
| 0046872 | |
| 0001649 | |
| 0005615 | |
| 0031988 |
| Pathway | PPARG Targets |
|---|---|
| VDR Targets |
| IPI ID | IPI00023015 |
|---|---|
| IPI00514336 | |
| IPI00197709 |
| Ariadne Ontology | ECM-Cell adhesion proteins |
|---|
| Mouse chromosome position | 3 42.6 cM |
|---|
| GO Molecular Function | hydroxyapatite binding |
|---|---|
| metal ion binding | |
| calcium ion binding | |
| structural constituent of bone |
| Homologene ID | 104130 |
|---|
| Hugo ID | 1043 |
|---|
| GO Cellular Component | extracellular region |
|---|---|
| extracellular space | |
| membrane-bounded vesicle |
| MGI ID | 88155 |
|---|---|
| 88156 | |
| 88157 |
| Human chromosome position | 1q25-q31 |
|---|
| GO Biological Process | cell adhesion |
|---|---|
| regulation of osteoclast differentiation | |
| regulation of bone mineralization | |
| regulation of bone resorption | |
| osteoblast differentiation | |
| ossification | |
| odontogenesis | |
| skeletal system development |
| Rat chromosome position | 2q34 |
|---|
| Group | ECM-Cell adhesion proteins |
|---|---|
| extracellular region | |
| extracellular space | |
| membrane-bounded vesicle | |
| hydroxyapatite binding | |
| metal ion binding | |
| calcium ion binding | |
| structural constituent of bone | |
| cell adhesion | |
| regulation of osteoclast differentiation | |
| regulation of bone mineralization | |
| regulation of bone resorption | |
| osteoblast differentiation | |
| ossification | |
| odontogenesis | |
| skeletal system development |
| RGD ID | 2206 |
|---|
| LocusLink ID | 632 |
|---|---|
| 12095 | |
| 12096 | |
| 12097 | |
| 25295 |
| Alias | OC |
|---|---|
| BGP | |
| PMF1 | |
| RP11-54H19.5 | |
| osteocalcin | |
| bone Gla protein | |
| OTTHUMP00000016586 | |
| gamma-carboxyglutamic acid-containing protein | |
| bone gamma-carboxyglutamate (gla) protein (osteocalcin) | |
| ORG | |
| mOC-X | |
| AI461847 | |
| MGC123552 | |
| bone gamma-carboxyglutamate protein, related sequence 1 | |
| OTTMUSP00000024825 | |
| OTTMUSP00000024826 | |
| OTTMUSP00000024831 | |
| OG1 | |
| Bglap | |
| mOC-A | |
| bone gamma carboxyglutamate protein 1 | |
| OTTMUSP00000024830 | |
| Og2 | |
| mOC-B | |
| OTTMUSP00000024832 | |
| Bgpr | |
| Bgpra | |
| Bglap2 | |
| bone Gla-protein | |
| bone gamma-carboxyglutamate protein 2 | |
| bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin) | |
| mOG2 | |
| Bglap1 | |
| Bglap-rs1 | |
| bone gamma-carboxyglutamate, related sequence | |
| bone gamma carboxyglutamate protein I | |
| bone gamma-carboxyglutamate protein II | |
| bone gamma-carboxyglutamate protein, related sequence I | |
| Bglap I | |
| DKFZp686G0786 | |
| bone gamma-carboxyglutamate protein | |
| Bglap-rs I | |
| Bone gamma-carboxyglutamic acid protein | |
| Bglap2s | |
| Bglap1s | |
| similar to RIKEN cDNA 9830147J24 | |
| hypothetical protein DKFZp686G0786 | |
| Bglap Is |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 112260 |
|---|