| URN | urn:agi-llid:793 |
|---|---|
| Name | CALB1 |
| Description | calbindin 1, 28kDa |
| Connectivity | 177 |
| Notes | Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. [provided by RefSeq] |
| Swiss-Prot Accession | B2R696 |
|---|---|
| P05937 | |
| O75552 | |
| A2AS59 | |
| P12658 | |
| Q8C5H2 | |
| Q8CEF3 | |
| P07171 |
| Unigene ID | Hs.65425 |
|---|---|
| Mm.277665 | |
| Rn.3908 |
| KEGG ID | hsa:793 |
|---|---|
| mmu:12307 |
| Swiss-Prot ID | CALB1_HUMAN |
|---|---|
| CALB1_MOUSE | |
| CALB1_RAT | |
| B2R696_HUMAN | |
| A2AS59_MOUSE |
| GO ID | 0005509 |
|---|---|
| 0005515 | |
| 0005499 | |
| 0007626 | |
| 0005737 | |
| 0005829 | |
| 0005634 | |
| 0007611 | |
| 0048167 | |
| 0042359 |
| Pathway | VDR Targets |
|---|
| IPI ID | IPI00220361 |
|---|---|
| IPI00331066 | |
| IPI00231118 |
| Mouse chromosome position | 4 10.5 cM |
|---|
| GO Molecular Function | protein binding |
|---|---|
| calcium ion binding | |
| vitamin D binding |
| Homologene ID | 21026 |
|---|
| Hugo ID | 1434 |
|---|
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol | |
| nucleus |
| MGI ID | 88248 |
|---|
| Human chromosome position | 8q21.3-q22.1 |
|---|
| GO Biological Process | regulation of synaptic plasticity |
|---|---|
| vitamin D metabolic process | |
| learning or memory | |
| locomotory behavior |
| Rat chromosome position | 5q13 |
|---|
| Group | cytoplasm |
|---|---|
| cytosol | |
| nucleus | |
| protein binding | |
| calcium ion binding | |
| vitamin D binding | |
| regulation of synaptic plasticity | |
| vitamin D metabolic process | |
| learning or memory | |
| locomotory behavior |
| RGD ID | 69340 |
|---|
| LocusLink ID | 793 |
|---|---|
| 12307 | |
| 83839 |
| Alias | CALB |
|---|---|
| calbindin 1 | |
| RTVL-H protein | |
| calbindin 1, (28kD) | |
| CB | |
| Calb-1 | |
| Brain-2 | |
| RP23-338J24.2 | |
| calbindin-28K | |
| OTTMUSP00000004961 | |
| calbindin 1, 28kDa | |
| CaBP28K | |
| MGC93326 | |
| calbindin D28 | |
| calbindin 1, 28 kD | |
| cerebellar Ca-binding protein spot 35 protein | |
| cerebellar Ca-binding protein, spot 35 protein | |
| vitamin D-dependent calcium-binding protein, avian-type | |
| 28 kDa calbindin 1 | |
| CALB1 | |
| Calbindin | |
| calcineurin regulatory chain | |
| D-28K | |
| Vitamin D-dependent calcium-binding protein-type 1 | |
| cerebellar Ca-binding, spot | |
| calbindin I | |
| Vitamin D-dependent calcium-binding protein-type I | |
| CAB27 | |
| CALB I | |
| 28 kDa calbindin I | |
| Calb protein | |
| Brain II |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 114050 |
|---|