| URN | urn:agi-llid:814 |
|---|---|
| Name | CAMK4 |
| Description | calcium/calmodulin-dependent protein kinase IV |
| Connectivity | 254 |
| Notes | The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq] |
| Swiss-Prot Accession | Q16566 |
|---|---|
| Q8BGR3 | |
| P08414 | |
| P13234 | |
| Q63082 | |
| Q6LED8 |
| Unigene ID | Hs.591269 |
|---|---|
| Mm.222329 | |
| Rn.11046 |
| KEGG ID | hsa:814 |
|---|---|
| mmu:12326 | |
| rno:25050 |
| EC Number | 2.7.1.123 |
|---|---|
| 2.7.11.17 |
| Swiss-Prot ID | KCC4_HUMAN |
|---|---|
| KCC4_RAT | |
| Q8BGR3_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0005524 |
|---|---|
| 0005509 | |
| 0005516 | |
| 0004683 | |
| 0000166 | |
| 0016740 | |
| 0006468 | |
| 0007165 | |
| 0005737 | |
| 0005634 | |
| 0016301 | |
| 0005515 | |
| 0004672 | |
| 0004674 | |
| 0016563 | |
| 0007270 | |
| 0006913 |
| Pathway | NeuropeptideYR -> ATF/CREB signaling |
|---|---|
| VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling | |
| VasopressinR2 -> MEF/MYOD/NFATC/MYOG signaling | |
| EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG signaling | |
| T-cell receptor -> CREBBP signaling | |
| VDR Targets |
| IPI ID | IPI00430411 |
|---|---|
| IPI00132526 | |
| IPI00874805 | |
| IPI00877328 | |
| IPI00231822 | |
| IPI00230883 |
| Ariadne Ontology | CAMK |
|---|
| Mouse chromosome position | 18 12.0 cM |
|---|
| GO Molecular Function | protein binding |
|---|---|
| nucleotide binding | |
| calcium ion binding | |
| ATP binding | |
| calmodulin binding | |
| transferase activity | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| calmodulin-dependent protein kinase activity | |
| transcription activator activity |
| Homologene ID | 100780 |
|---|
| Hugo ID | 1464 |
|---|
| GO Cellular Component | cytoplasm |
|---|---|
| nucleus |
| MGI ID | 88258 |
|---|
| Human chromosome position | 5q21.3 |
|---|
| GO Biological Process | signal transduction |
|---|---|
| nerve-nerve synaptic transmission | |
| nucleocytoplasmic transport | |
| protein amino acid phosphorylation |
| Rat chromosome position | 18p12 |
|---|
| Group | CAMK |
|---|---|
| cytoplasm | |
| nucleus | |
| protein binding | |
| nucleotide binding | |
| calcium ion binding | |
| ATP binding | |
| calmodulin binding | |
| transferase activity | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| calmodulin-dependent protein kinase activity | |
| transcription activator activity | |
| signal transduction | |
| nerve-nerve synaptic transmission | |
| nucleocytoplasmic transport | |
| protein amino acid phosphorylation |
| RGD ID | 2264 |
|---|
| LocusLink ID | 814 |
|---|---|
| 12326 | |
| 25050 |
| Alias | CaMK-GR |
|---|---|
| MGC36771 | |
| calcium/calmodulin-dependent protein kinase IV | |
| CAM kinase IV | |
| CAM kinase- GR | |
| brain Ca++-calmodulin-dependent protein kinase type IV | |
| brain Ca(2+)-calmodulin-dependent protein kinase type IV | |
| calcium/calmodulin-dependent protein kinase type IV catalytic chain | |
| CaMKIV | |
| AI666733 | |
| CaMKIV/Gr | |
| D18Bwg0362e | |
| A430110E23Rik | |
| Ca2+/calmodulin-dependent protein kinase type IV/Gr | |
| Ccdpk | |
| RATCCDPK | |
| Calmodulin-dependent protein kinase IV | |
| CaMK IVs | |
| CaMK-GRs | |
| Ca(2+)-calmodulin-dependent protein kinase type IV of brain | |
| CAM kinase 4 | |
| CaMK IV | |
| CAMK4 | |
| calmodulin-dependent protein kinase 4 | |
| CaM-KIV | |
| RIKEN cDNA A430110E23 gene |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 114080 |
|---|